UCN3 and malignant colon neoplasm: Based on these findings we postulate that the stress neuropeptide Ucn3 present in the vicinity of tumors (either produced locally by the tumor cells themselves or by nearby normal cells or secreted from the innervations of surrounding tissues) could promote an EMT-like process and play an important role on colon cancer cell metastatic capacity, providing a potential link between stress and tumor progression.