Nevertheless, 7 of the PP-increased DEGs were associated with psoriasis susceptibility loci (LCE3D, IFIH1, GRHL3, IL12B, PRSS53, REL and NOS2), and 1 PP-decreased DEG was near a psoriasis susceptibility locus (SDC4) (Figure S7). This evidence concerns the gene GRHL3 and psoriasis.