We identified a motif resembling the interferon-stimulated response element (ISRE) enriched in genome regions near STAT1-57 genes (i.e., G(A/G)AANNGAAA(C/G)T) (Figure 6), and most of the STAT1-57 genes strongly increased in psoriasis lesions featured this motif near the TSS (Figure 6E). The gene discussed is STAT1; the disease is psoriasis.