Chronic myeloid leukemia (CML) and Ph+ acute lymphoblastic leukemia (Ph+ ALL) are characterized by the presence of the BCR-ABL oncoprotein, the product of the Philadelphia chromosome (Ph) resulting from the aberrant translocation between chromosomes 9 and 22 [1], [2]. The gene discussed is BCR; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.