More specifically, we focused on a select number of SATB1 target genes that are known to participate in tumorigenesis and metastasis (e.g. tumor/metastasis suppressors BRMS1, Kiss1, Claudin-1; tumor/metastasis promoters c-Abl, MMP3, ErbB2 and Snail). The gene discussed is KISS1; the disease is neoplasm.