ERBB2 and gastric carcinoma: Therefore, the present study analyzed the HER2 status in a cohort of 304 surgical cases of advanced/metastatic gastric carcinomas that were obtained from the archives of 10 Sicilian anatomopathological units, in order to verify the positive rate of HER2-positive cases, taking into consideration the characteristics of the histotype, grade, stage and Ki-67 expression.