TP53 and malignant colon neoplasm: NDRG1 phosphorylation by the protein kinase, SGK1, was found to be increased basally in p53-deficient cells and to co-localize with γ-tubulin on centromeres and to the cleavage furrow during cytokinesis (22), which indicates that NDRG1 is important in successful colon cancer mitosis.