BCR/ABL is derived from chromosomal translocation (relocation of the portion of c-ABL gene from chromosome 9 to the portion of BCR gene locus on chromosome 22 t (9;22)), yielding the Philadelphia (Ph) chromosome that is present in over 90% of CML [2,3]. This evidence concerns the gene ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive.