The proportion of GST mu 1 (GSTM1)-null genotypes was significantly higher in patients with COPD than in controls in a Taiwanese population 29, while there was no difference in the frequency of polymorphic genotypes of GST theta 1 (GSTT1) and GST P1 (GSTP1). The gene discussed is GSTP1; the disease is chronic obstructive pulmonary disease.