ALB and Nephropathy: Because nephropathy was not a clear-cut clinical entity, many biomarkers for early detection of Cd induced renal dysfunction such as NAG, albumin, β2-MG, α1-MG etc. had been used in several studies (Jung et al. 1993; Jin et al. 2002; Moriguchi et al. 2003; Teeyakasem et al. 2007).