MUC16 and hydrops fetalis: Additionally, the possible translocation of bacteria or endotoxin formation during the exacerbation of HF, a condition most likely to happen in subjects presenting with right heart failure as well as gastrointestinal functional impairment in the context of bowel congestion with HF, may also play a key role in the “hyper-response” of CA-125 from mesothelium [37].