These genes selected have crucial roles involved in cell cycle arrest (p15, p16, p57 and LATS-2), apoptosis (TMS1, APAF-1, DAPK and DIABLO), differentiation regulation (NES-1), cell adhesion and metastasis process (CDH1, CDH13, ADAMTS1 and ADAMTS5), tumor suppression (LATS-1 and PTEN), WNT pathway (DKK-3, WIF-1, sFRP-1, sFRP-2, sFRP-4 and sFRP-5), JAK-STAT pathway (PTPN6 (SHP-1)), p53 pathway (p14, p73 and PPP1R13B (ASPP-1)), ubiquitination (PARK-2) and tyrosine kinase (SYK). The gene discussed is CDKN2A; the disease is neoplasm.