The strongest signal comes from single nucleotide polymorphism (SNP) rs7571971 that is within EIF2AK3. There are several non-synonymous coding polymorphisms in EIF2AK3 that track with risk and EIF2AK3 appears to be the gene in this region involved in PSP. This evidence concerns the gene EIF2AK3 and supranuclear palsy, progressive, 1.