In addition, CXC chemokines (including gro-α) that are secreted by endothelial cells can induce tumor cell invasion, whereas the blockade of the gro-α receptor CXCR2 can inhibit the invasion of oral squamous cell carcinoma-3 and Kaposi’s sarcoma cells into endothelial cells [40]. Here, CXCL1 is linked to neoplasm.