TARDBP and mild neurocognitive disorder: Pathologically, most FTLD cases with the expansion [15-20], like many non-mutational cases of FTLD [2,21,22], show inclusion bodies within neurones (NCI) and glial cells of the cerebral cortex and hippocampus that contain the nuclear transcription factor, TDP-43, and are said bear a TDP-43 histological subtype termed FTLD-TDP type B (according to [23]), compatible with a clinical diagnosis of FTD and MND.