Among the 3 subjects with IBM presentation (designated by open symbols in Figure 4), all 3 subjects exceeded the IBM 100% specificity threshold for LC3, 2 subjects exceeded the IBM 100% specificity threshold for p62, and 1 subject (#33, shown in Figures 3f-j) exceeded the IBM 100% specificity threshold for TDP-43. The gene discussed is SQSTM1; the disease is inclusion body myositis.