LGR5 and medulloblastoma: For example, in two cohorts of subtyped medulloblastoma tumors (188 medulloblastomas and 11 control cerebella [8], and 103 medulloblastomas [10]), both LGR5 and GPR64 were found to be expressed at higher levels in the WNT subgroup tumors, as compared to both normal cerebella and the other three subgroups of tumors (Figure 3a-d); these expression characteristics support our results (Additional file 3: Table S2).