Urinary cystatin C levels were identified as an independent factor associated with estimated glomerular filtration rate (eGFR) < 60ml/min/1.73m2 in patients with normoalbuminuria, which indicated urinary cystatin C levels could be a useful marker for renal dysfunction in type 2 diabetic patients with normoalbuminuria[11]. The gene discussed is CST3; the disease is Abnormal renal physiology.