KRT18 and metabolic dysfunction-associated steatohepatitis: Plasma CK18 fragments were found to be markedly increased in patients with NASH (n=21) than those with simple steatosis (n=8) or normal controls (n=10) [median (interquartile range): 765.7 U/L (479.6-991.1), 202.4 U/L (160.4-258.2), 215.5 U/L (150.2-296.2), respectively; p < 0.001] [41].