APOE and epilepsy: This analysis showed that there was less oxidative damage to DNA in tissue from epilepsy patients with genotypes other than APOE ε4,4 (55 ± 6 and 55 ± 6 vs 80 ± 3 arbitrary units, respectively, p < 0.01) (Figure 5), even though this indication of cellular stress is not necessarily followed by DNA fragmentation [19].