Using RT-qPCR techniques, expression levels of MCP-1 and CCR2 mRNA in lumbar spinal cords from G1H+/− (ALS mice) and SJL (control mice) mice were quantitatively compared between the presymptomatic (9-weeks-old mice), onset (12-weeks-old mice), and postsymptomatic (15-weeks-old mice) groups. This evidence concerns the gene CCR2 and amyotrophic lateral sclerosis.