MOG and viral infectious disease: There are some evidence that support the role of myelin base protein (MBP), proteolipid protein (PLP), and myelin oligodendrocytes glycoprotein (MOG) in inducing immune responses.2 Viral infection, including human herpes virus 6, Epstein-Barr virus, varicella-zoster virus, and herpes simplex virus are thought to be second trigger factors.