IL6 and myeloid sarcoma: Adipose tissue secretes cytokines that influence the immune system function, including leptin, and interleukin-6, both of which have been shown to reduce regulatory T cell activity.24–27 The elevation of leptin levels were inversely correlated with frequency of regulatory T cells in MS patients.4 There are several studies which suggest the pathogenesis of the effects of leptin hormone in MS patients.5, 6, 22, 28