Consistent with these results, a major increase in TUNEL positivity was observed for both ascites-derived BC-3 and BCBL-1 cells treated with arsenic/IFN or AZT/IFN combinations (p< 0.001), whereas minimal effects were seen with single agent treatments (Figure 3C, p< 0.05, Figure S3B). The gene discussed is IFNA1; the disease is breast cancer.