USH1C and immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome: Considering that the main histopatological feature of the IPEX enteropathy is villous atrophy with apoptotic cell death of enteric epithelial cells in association with moderate to marked inflammation [13], it is likely that in this context harmonin and villin might act as a relevant molecular targets of pathogenic autoimmunity.