Regarding aortic lipid peroxidation markers (Table 1), STZ-induced diabetes resulted in an elevation of MDA content and decreased SOD activity (p < 0.005-0.001) in aortic tissue and chronic treatment of diabetic group with sesame seed at a weight ratio of 6% significantly reversed the increased MDA content and restored activity of SOD (p < 0.05). This evidence concerns the gene SOD1 and diabetes mellitus.