APOA1 and Insulin resistance: However, we found no signifcant difference in HDL-c, homocysteine and HbA1c but LDL-c/HDL-c, TG/HDL-c, apoB/apoA-I and insulin resistance had significant decreases at the end of study in BRFE group compared to the placebo group (p = 0.001, p = 0.003, p = 0.01, and p = 0.01) (Table 3).