Chronic treatment with haloperidol decanoate (30 mg and 50 mg i.m. every 3 weeks, about half the actual number of milligrams used in treating schizophrenia in humans) protected striatal neurons from mutant huntingtin-related dysfunction and extranuclear huntingtin aggregation at both 2 and 8 weeks of treatment in rats transfected with lentivirus expressing mutant HTT171-82Q [161]. The gene discussed is HTT; the disease is schizophrenia.