Carmichael et al. found the mood stabilizer lithium at 2.5–5 mM for 3 days (2–5 times human therapeutic plasma levels) to reduce mutant huntingtin nuclear inclusions and apoptotic nuclear fragmentation in COS-7 African green monkey kidney cells and SKNSH human neuroblastoma cell lines transfected with mutant HTT exon 1 fragment possessing 74 CAG repeats [38]. Here, HTT is linked to neuroblastoma.