Expression of claudin-6 was 69.4c/o (25/36) in the ovarian carcinomas and 34.6c/o (9/26) in the ovarian serous adenomas and expression of claudin-6 in ovarian papillary serous carcinomas significantly was significantly higher than that in ovarian serous adenomas (Table 1, Figure 1A and 1B, chi-square test χ2 = 7.3946, P = 0.0065). The gene discussed is CLDN6; the disease is ovarian carcinoma.