In agreement with our findings, a recent study reported that amlodipine profoundly reduced incidence of abdominal and thoracic aortic aneurysms in normocholesterolemic mice co-administered either AngII or deoxycorticosterone acetate-salt with a lysyl oxidase inhibitor, beta-aminopropionitrile [54]. This evidence concerns the gene LOX and thoracic aortic aneurysm.