YTHDF1 and 22q11.2 deletion syndrome: Mouse models of 22q11DS such as the Df1/+ mouse have attracted great interest not only as a tool for investigating the origins of various defects and disabilities associated with this relatively common chromosomal disorder, but also as a means of gaining insight into the pathogenesis of schizophrenia, for which 22q11DS is one of the most significant known risk factors.