GPR68 and asthma: Although our asthma model suggests that the stimulation of OGR1 in DCs by a physiological or mildly acidic pH is critical for the onset of asthmatic responses by regulating their migration, an earlier step in asthmatic responses, this does not mean that OGR1 is not involved in the exacerbation of asthma by severe airway acidification, which has been shown to be associated with the late phase of an asthmatic situation [3-5].