Following administration of Myelin Oligodendrocyte Glycoprotein Peptide (MOG) peptide emulsified in complete Freund’s adjuvant, myelin-reactive Th17 cells will undergo activation in lymph nodes and cross the blood-brain barrier, initiating an inflammatory cascade in the central nervous system which will lead to neuronal degeneration and gradual limb paralysis. The gene discussed is MOG; the disease is Paralysis.