Among these 40 splicing factors, SRSF11 showed isoform switching in 7 of 20 MDS samples (Figure 2A), including 4 RAEBs used to build our model, one RCMD, one AML with MDS and one MDS for which the subtype is unknown. This evidence concerns the gene SRSF11 and myelodysplastic syndrome with multilineage dysplasia.