There were no differences in these Treg frequencies in leprosy patients versus HHC (CD4+ Treg, 18.70±6.77 vs. 13.79±8.19%, p = 0.0996 and CD8+ Treg, 10.29±7.57 vs. 6.18±5.56%, p = 0.1033, data not shown). The gene discussed is CD8A; the disease is leprosy.