In the comparison of LP cells of typical NLPHL with tumor cells of THRLBCL, the highest number of differentially expressed genes was observed; 16 genes were upregulated more than 1.7-fold in the LP cells of typical NLPHL, including HIGD1A (upregulated 2.0-fold, Table 1, Table S3). This evidence concerns the gene HIGD1A and neoplasm.