PTGS2 and amnesia: Pharmacologically, pretreatment with propofol, which potentiates γ-aminobutyric acid receptor A (GABAA receptor) activity and blocks sodium channels, selective glucocorticoid antagonists and selective non-steroidal anti-inflammatory cyclooxygenase-2 inhibitors, all attenuate the amnesia effect of ECS in animal models [56]–[59].