Nevertheless, UCHL1 and FBXO7 interact with ParkinIP proteins, and therefore the RelatedPD subnetwork consists of a single connected component when ATP13A2, which is responsible for Kufor-Rakeb syndrome, a form of parkinsonism with dementia and juvenile disease onset [22], is excluded. Here, ATP13A2 is linked to parkinsonism due to ATP13A2 deficiency.