EDNRA and Hypertension: Take the most confident prediction as an example, target protein ‘Endothelin-1 receptor’ (EDNRA) for ‘Bosentan’, and the disease gene ‘KCNMB1’ (Kca) for ‘Hypertension, Diastolic, Resistance To’ belong to the same pathway ‘Arachidonic Acid metabolism’ (Figure 8).