Based on the finding that CD4+ and CD8+ T cells produced IL-10 after Clone 13 infection (Figure 1D) and that CD4+ T cell depletion decreased IL-10 mRNA levels on day 5 post infection (Figure 2F), we investigated if T cell derived IL-10 complements macrophage derived IL-10 to exert it's biological effects. This evidence concerns the gene CD8A and infection.