As neutrophils and macrophages produce IL-10 on day 2 and 5 post infection (Figure 1D and E) and as monocyte/macrophage depletion reduced the overall IL-10 mRNA levels (Figure 2D and H), Il-10fl/flxLysM-Cre+ mice, in which selectively myeloid cells lack IL-10 production, were infected with Clone 13. The gene discussed is IL10; the disease is infection.