TNF and infection: In line with this, a higher percentage and total number of TNF-α producing T cells was observed in the spleens and lungs of Il-10fl/flxLysM-Cre+ mice which could control the infection compared to Cre negative littermate controls, the Il-10fl/flxLysM-Cre+ mice which could not control the infection and C57BL/6 mice (Figure 6E–J).