However, in ESCC the chimera GOLM1-MAK10 appears to be highly enriched while the two most prominent prostate cancer chimeric RNA, SLC45A3-ELK4 and TMEM79-SMG5 [6], and the fusion transcript from the prostate cancer fusion gene TMPRSS2-ERG [22], are undetectable in ESCC (Figure 2), indicating that the different cancer types posses different prominent molecular signatures with respect to chimeric RNA species. Here, SLC45A3 is linked to Familial prostate cancer.