HMOX1 and neoplasm: We show that lipid trafficking between marrow adipocytes and cancer cells fuels tumor growth and invasiveness by upregulating FABP4, as well as interleukin 1β (IL-1β), cytokine linked to tumor growth, invasiveness, and metastatic potential [35-37] and its target gene, oxidative stress protein, heme oxygenase 1 (HMOX-1)[38-41], a process that can be blocked by FABP4 inhibition.