APOH and autoimmune disease: Ox-LDL/beta2-GPI complexes were found in patients that suffer autoimmune diseases [24], diabetes [25], etc. Autoantibodies further combined with beta2-GPI in the complexes to form ox-LDL/beta2-GPI/autoantibody complexes (actually antigen/antibody complexes), which could be phagocytised by macrophages, and actually increased ox-LDL intake and foam cell formation [20,24,26].