Recently, He et al. reported that 14-3-3 zeta protein represents a candidate biomarker and a metastasis-promoting factor in ovarian cancer based on a serum proteomic analysis of a nude mouse xenograft model containing SKOV-3 cells and a mass spectrometry [liquid chromatography-tandem mass spectrometry (LC-MS/MS)] analysis to identify metastasis-related serum proteins [10]. The gene discussed is YWHAZ; the disease is ovarian carcinoma.