From this set, eight lncRNAs were identified as altered in both the malignancy and the survival outcome expression profiles, and they are transcribed from the loci: ACTN4, CSNK1D, DNAJC3, GIGYF2, HDAC5, PTPN3, RAB25 and VPS13B. To the best of our knowledge, this is the first study suggesting lncRNAs as correlated to the patient survival outcome in RCC. This evidence concerns the gene HDAC5 and renal cell carcinoma.