Furthermore, analysis of the published array data supplied by Kautz et al (2008) for iron loaded and iron deficient mouse liver (Data available at the National Center for Biotechnology Information [NCBI] Geo database (Edgar et al, 2002), accession GSE10421) in C57 and DBA strains shows that liver Usf1 mRNA was not iron-regulated in either strain whereas Usf2 mRNA was decreased by iron loading in both strains of mice but also decreased in iron deficiency. This evidence concerns the gene USF2 and Iron deficiency anemia.