For example, our machine-based GBM classification recognized a subset of patients with high oligodendroglioma component (MOC 2) that showed a statistically significant overexpression of genes known to be tightly associated with oligodendrocytes, including MOBP (encoding myelin-associated oligodendrocyte basic protein) and MBP (encoding myelin basic protein, the major protein of the myelin sheath). This evidence concerns the gene MOBP and oligodendroglioma.