According to our Kaplan-Meier estimate, PAK1 overexpression in GEJ adenocarcinoma was correlated with shorter overall survival, which is agreed by previous studies that PAK1 overexpression is correlated with a decreased overall survival in gastric, colorectal, hepatocellular and breast cancer patients [21], [61]–[63]. This evidence concerns the gene PAK1 and gastroesophageal junction adenocarcinoma.