Interestingly, situations that have been potentially associated with vascular homeostasis either in in vitro cell studies or in vivo animal models, such as changes in pH, hydrogen peroxide, inorganic phosphate, hypertension, and atherosclerosis, all appear to be affected by Gas6 and/or Axl expression, but the influence is inconsistent [9], [13], [27], [28]. This evidence concerns the gene AXL and hypertensive disorder.