Interestingly, of the 9 TF-binding sites identified, 5 (v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (MYCN); v-myc myelocytomatosis viral oncogene homolog (MYC); upstream transcription factor 1 (USF1); aryl hydrocarbon receptor nuclear translocator (ARNT); v-myb myeloblastosis viral oncogene homolog (MYB)) were located within 100 bp upstream of the TSS in a highly conserved approximately 265 bp region that encompassed both the TSS and CGI (Figure 3B). This evidence concerns the gene TF and neuroblastoma.