Deficient function of the α2- or α3-isoform of the Na+/K+-ATPase, caused by mutations in the genes ATP1A2 or ATP1A3, is associated with the neurological diseases hemiplegic migraine (HM) and rapid-onset dystonia parkinsonism (RDP), respectively [20]–[22]. The gene discussed is ATP1A3; the disease is nervous system disorder.